Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210169 | 0.93 | TDP1 (0.68) | TDP1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL5842593 | 0.83 | ALDH1A1 (0.62) | TDP1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL2677328 | 0.82 | CHRM2 (0.60) | TDP1ALDH1A1HPGDGAAMEN1 | |
| SCHEMBL1520429 | 0.81 | TDP1 (0.72) | TDP1ALDH1A1MAPTCYP1A2GAA | |
| SCHEMBL2434485 | 0.80 | ALDH1A1 (0.57) | TDP1ALDH1A1MAPTHPGDCYP1A2 | |
| SCHEMBL9830719 | 0.79 | ALDH1A1 (0.54) | TDP1ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL2677706 | 0.79 | TP53 (0.61) | ALDH1A1HPGDNPC1RAB9AGAA | |
| SCHEMBL9953947 | 0.79 | HTT (0.55) | TDP1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL2677428 | 0.78 | GAA (0.61) | TDP1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL10860276 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173705-B2 | Agent for alleviating wrinkles | SHISEIDO COMPANY LTD. (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20100113450-A1 | Agent for Preventing and Alleviating Wrinkles | SHISEIDO COMPANY LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2123253-A1 | WRINKLING-PREVENTING AND -MODIFYING AGENT | Shiseido Company, Ltd. (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113450-A1 | Agent for Preventing and Alleviating Wrinkles | GABRB1, GABRB2, GABBR1 | TDP1 1395/4885ALDH1A1 392/4885MAPT 2244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.