SCHEMBL2676992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25254856	0.82	APEX1 (0.49)	KMT2AAPEX1ALDH1A1LMNAGAA
	SCHEMBL2677906	0.75	NOS1 (0.44)	KMT2AALDH1A1LMNAGAALTK
	SCHEMBL2678404	0.73	ALDH1A1 (0.38)	APEX1ALDH1A1AURKACSF1RRET
	SCHEMBL16751925	0.72	ALDH1A1 (0.34)	ALDH1A1LMNALTKCSNK1A1CDK8
	SCHEMBL4769662	0.72	IKBKB (0.34)	ALDH1A1LMNALTKCSNK1A1CDK8
	SCHEMBL3383806	0.72	ALDH1A1 (0.38)	ALDH1A1LMNAGAALTKCSNK1A1
	SCHEMBL31675965	0.71	ALDH1A1 (0.55)	KMT2AALDH1A1LMNAGAAIKBKB
	SCHEMBL3000943	0.71	SMN1; SMN2 (0.45)	KMT2AALDH1A1LMNAGAADHODH
	SCHEMBL1938667	0.69	CA12 (0.37)	KMT2ALTKCSNK1A1CDK8CLK2
	SCHEMBL25457532	0.69	APEX1 (0.34)	KMT2AAPEX1ALDH1A1LMNAAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.