Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24620351 | 0.78 | MAP4K1 (0.51) | MAP4K1PTK2ALKWEE1BTK | |
| SCHEMBL30411397 | 0.78 | PTK2 (0.44) | MAP4K1PTK2FLT4 | |
| SCHEMBL25199604 | 0.78 | PTK2 (0.44) | MAP4K1PTK2FLT4 | |
| SCHEMBL30412232 | 0.78 | MERTK (0.43) | MAP4K1PTK2BTKTYRO3MERTK | |
| SCHEMBL30411174 | 0.78 | MERTK (0.43) | MAP4K1PTK2BTKTYRO3MERTK | |
| SCHEMBL25205416 | 0.78 | MERTK (0.43) | MAP4K1PTK2BTKTYRO3MERTK | |
| SCHEMBL25204972 | 0.78 | MERTK (0.43) | MAP4K1PTK2BTKTYRO3MERTK | |
| SCHEMBL30411785 | 0.77 | LRRK2 (0.42) | MAP4K1PTK2FLT4LRRK2TYRO3 | |
| SCHEMBL25205942 | 0.77 | LRRK2 (0.42) | MAP4K1PTK2FLT4LRRK2TYRO3 | |
| SCHEMBL25210979 | 0.77 | MAP4K1 (0.40) | MAP4K1PTK2FLT4WEE1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215494-A1 | THIOPHENE ULK1/2 INHIBITORS AND THEIR USE THEREOF | ERASCA, INC. (US) | 2023-11-09 | — | — | WO | disclosed |