Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 18/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26773189 | 0.89 | KDM4E (0.43) | PSMB5KDM4ELMNAMAPK1HTT | |
| SCHEMBL26779100 | 0.75 | CA12 (0.42) | KDM4ELMNAL3MBTL1CA12CA1 | |
| SCHEMBL26773187 | 0.73 | KDM4E (0.49) | PSMB5KDM4EMAPK1HTT | |
| SCHEMBL11029836 | 0.67 | CA12 (0.41) | KDM4ELMNAL3MBTL1CA12CA1 | |
| SCHEMBL20125953 | 0.66 | CA12 (0.40) | KDM4ELMNACA12CA1CA2 | |
| SCHEMBL9368682 | 0.66 | NLRP3 (0.40) | MAPK1L3MBTL1CA12CA1CA2 | |
| SCHEMBL9425009 | 0.66 | SMN1; SMN2 (0.43) | KDM4EHTTL3MBTL1 | |
| SCHEMBL11265878 | 0.65 | CA12 (0.48) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL26773201 | 0.65 | CA12 (0.39) | KDM4ELMNACA12CA1CA2 | |
| SCHEMBL18796463 | 0.65 | CA12 (0.39) | HTTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |