Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321389 | 1.00 | P2RX7 (0.46) | P2RX7ATMLMNACTSK | |
| SCHEMBL25907518 | 1.00 | P2RX7 (0.46) | P2RX7ATMLMNACTSK | |
| SCHEMBL25321397 | 1.00 | P2RX7 (0.46) | P2RX7ATMLMNACTSK | |
| SCHEMBL25907516 | 0.81 | ATM (0.50) | ATMCTSK | |
| SCHEMBL30550771 | 0.81 | ATM (0.50) | ATMCTSK | |
| SCHEMBL13303252 | 0.79 | ATM (0.48) | ATMCTSK | |
| SCHEMBL26782892 | 0.78 | ATM (0.47) | ATMCTSK | |
| SCHEMBL8539453 | 0.77 | P2RX7 (0.48) | P2RX7LMNA | |
| SCHEMBL8539455 | 0.77 | P2RX7 (0.48) | P2RX7LMNA | |
| SCHEMBL9466546 | 0.76 | ALDH1A1 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365529-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365529-A1 | PARP7 INHIBITORS | PARP1, PARP11, PARP2 | P2RX7 661/4885ATM 206/4885LMNA 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.