Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916154 | 0.98 | ALDH1A1 (0.77) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL16564081 | 0.95 | ALDH1A1 (0.81) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL30602595 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL433102 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL3101921 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL17256326 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL16387329 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL14921878 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL31005435 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL7153037 | 0.82 | HPGD (0.70) | ALDH1A1KMT2AMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013861-A1 | ANTI-FCRH5 ANTIBODIES | Genentech, Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| EP-2962697-A1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | diaDexus, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-2104513-B1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS INC (US) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014210064-A1 | ANTI-FCRH5 ANTIBODIES | GENENTECH, INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-20130224776-A1 | PCan065 Antibody Compositions and Methods of Use | DIADEXUS, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130022539-A1 | OVR115 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-20120329079-A1 | Pro108 Antibody Compositions and Methods of Use and Use of Pro108 to Assess Cancer Risk | DIADEXUS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| EP-1817055-B1 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS INC (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120263647-A1 | Pro104 Antibody Compositions and Methods of Use | DIADEXUS, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| US-8173434-B2 | PCan065 antibody compositions and methods of use | DIADEXUS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| EP-1646357-A2 | PRO104 ANTIBODY COMPOSITIONS AND METHODS OF USE | Diadexus, Inc. (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1633850-A2 | Ovr115 ANTIBODY COMPOSITION AND METHODS OF USE | Diadexus, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| EP-1633784-A2 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | Diadexus, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2006010077-A2 | PRODRUGS OF LONIDAMINE AND LONIDAMINE ANALOGS | THRESHOLD PHARMACEUTICALS, INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2005095454-A1 | LNG105 ANTIBODY COMPOSITION AND METHODS OF USE, AND USE OF LNG105 TO ASSESS LUNG CANCER RISK | DIADEXUS, INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| US-20050124012-A1 | Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk | DIAZYME LABORATORIES, INC. | 2005-06-09 | — | — | US | disclosed |
| WO-2005046573-A2 | Pro104 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005021709-A2 | CLN101 ANTIBODIES | DIADEXUS, INC. (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-2004104173-A2 | Ovr115 ANTIBODY COMPOSITION AND METHODS OF USE | DIADEXUS, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004101756-A2 | OVR110 ANTIBODY COMPOSITIONS AND METHODS OF USE | DIADEXUS, INC. (US) | 2004-11-25 | — | — | WO | disclosed |