Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550965 | 0.87 | ELANE (0.52) | ELANEALDH1A1RAB9AMEN1GAA | |
| SCHEMBL26784171 | 0.79 | ELANE (0.44) | ELANEALDH1A1RAB9AMEN1GAA | |
| SCHEMBL5431999 | 0.73 | RAB9A (0.51) | ELANEALDH1A1RAB9AMEN1GAA | |
| SCHEMBL16280099 | 0.71 | MGLL (0.62) | ESR1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL15437877 | 0.70 | ESR1 (0.47) | ESR1ALDH1A1NR1H3MEN1GAA | |
| SCHEMBL142042 | 0.68 | ELANE (0.41) | ESR1ELANEALDH1A1RAB9AMEN1 | |
| 3,4-Dimethylphenylmaleimide SCHEMBL5074358 | 0.68 | PARP1 (0.53) | ESR1ELANEALDH1A1GAAKDM4E | |
| SCHEMBL15203010 | 0.67 | CDC25A (0.53) | ELANEALDH1A1RAB9AMEN1GAA | |
| SCHEMBL30758581 | 0.67 | NR1H3 (0.62) | ALDH1A1RAB9ANR1H3MEN1GAA | |
| SCHEMBL13412864 | 0.67 | NR1H3 (0.62) | ALDH1A1RAB9ANR1H3MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807639-B1 | Pyrrolo[3,4-b]quinoline compounds as antibacterial agents | King Faisal University (SA) | 2023-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11807639-B1 | Pyrrolo[3,4-b]quinoline compounds as antibacterial agents | POLB, TOP2A, POLI | ESR1 4125/4885ELANE 2611/4885ALDH1A1 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.