Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26785585 | 0.85 | KCNQ3 (0.61) | NPC1ALDH1A1RAB9AKDM4EP4HTM | |
| SCHEMBL12894452 | 0.83 | RAB9A (0.60) | NPC1ALDH1A1RAB9AKDM4EP4HTM | |
| SCHEMBL6686328 | 0.80 | ALDH1A1 (0.71) | NPC1ALDH1A1RAB9AKDM4EP4HTM | |
| SCHEMBL30834320 | 0.79 | ALDH1A1 (1.00) | NPC1ALDH1A1RAB9AKDM4EP4HTM | |
| SCHEMBL13210581 | 0.79 | ALDH1A1 (1.00) | NPC1ALDH1A1RAB9AKDM4EP4HTM | |
| SCHEMBL12017909 | 0.79 | BAZ2B (0.53) | P4HTMHDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL12894455 | 0.78 | ALDH1A1 (0.48) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL21401430 | 0.78 | GRM5 (0.54) | ALDH1A1HDAC6LMNA | |
| SCHEMBL30043919 | 0.77 | HCAR3 (0.56) | ALDH1A1P4HTM | |
| SCHEMBL100969 | 0.77 | HCAR3 (0.56) | ALDH1A1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814388-B1 | Substituted pyrrolo[2,3-d]pyrimidines and pyrazolo[3,4-d]pyrimidines as inhibitors for multi-resistant cancers | FERRIS STATE UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814388-B1 | Substituted pyrrolo[2,3-d]pyrimidines and pyrazolo[3,4-d]pyrimidines as inhibitors for multi-resistant cancers | FERRIS STATE UNIVERSITY (US) | 2023-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814388-B1 | Substituted pyrrolo[2,3-d]pyrimidines and pyrazolo[3,4-d]pyrimidines as inhibitors for multi-resistant cancers | AURKA, AURKC, AURKB | NPC1 2657/4885ALDH1A1 3855/4885RAB9A 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.