Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14388278 | 0.82 | — | — | |
| SCHEMBL22387991 | 0.77 | PIK3CD (0.53) | PIK3CD | |
| SCHEMBL12448119 | 0.71 | KDM4E (0.31) | KCNH2HRH3 | |
| SCHEMBL12027034 | 0.71 | KDM4E (0.31) | PIK3CDKCNH2HRH3 | |
| SCHEMBL14477695 | 0.69 | PIK3CD (0.59) | PIK3CD | |
| SCHEMBL13187599 | 0.68 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL13870227 | 0.68 | PIK3CD (0.52) | PIK3CD | |
| SCHEMBL20438383 | 0.67 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL10254882 | 0.66 | — | — | |
| SCHEMBL14885170 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827656-B2 | Immunoproteasome inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827656-B2 | Immunoproteasome inhibitors | PSMC2, PSMB7, PSMB2 | PIK3CD 3272/4885KCNH2 4094/4885HRH3 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.