Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6515355 | 0.86 | ALDH1A1 (0.46) | NPSR1RIPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL2677617 | 0.82 | NPSR1 (0.60) | NPSR1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL6123646 | 0.81 | ALDH1A1 (0.49) | NPSR1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL15330119 | 0.81 | KMT2A (0.42) | NPSR1ALDH1A1MAPK14KCNN4KMT2A | |
| SCHEMBL15331113 | 0.80 | HPGD (0.39) | NPSR1ALDH1A1NPC1RAB9AKCNN4 | |
| SCHEMBL20578432 | 0.79 | HPGD (0.46) | NPSR1ALDH1A1NPC1RAB9AKCNN4 | |
| SCHEMBL14161878 | 0.78 | CNR1 (0.48) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2552256 | 0.77 | KCNN4 (0.37) | ALDH1A1NPC1RAB9AMAPK14KCNN4 | |
| SCHEMBL2563102 | 0.77 | GAA (0.38) | KCNN4KMT2AHPGDGAA | |
| SCHEMBL15329895 | 0.77 | KMT2A (0.39) | RIPK1ALDH1A1NPC1RAB9AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173680-B2 | Cannabinoid receptor modulators | 7TM PHARMA A/S (DK) | 2012-05-08 | — | — | US | disclosed |
| US-8173680-B2 | Cannabinoid receptor modulators | 7TM PHARMA A/S (DK) | 2012-05-08 | — | — | US | disclosed |
| US-8173680-B2 | Cannabinoid receptor modulators | 7TM PHARMA A/S (DK) | 2012-05-08 | — | — | US | disclosed |
| US-20100292273-A1 | Cannabinoid Receptor Modulators | 7TM PHARMA A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| US-20100292273-A1 | Cannabinoid Receptor Modulators | 7TM PHARMA A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| US-20100292273-A1 | Cannabinoid Receptor Modulators | 7TM PHARMA A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| EP-2231615-A1 | CANNABINOID RECEPTOR MODULATORS | 7TM Pharma A/S (DK) | 2010-09-29 | — | — | EP | disclosed |
| EP-2120931-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CANNABINOID RECEPTOR | 7TM Pharma A/S (DK) | 2009-11-25 | — | — | EP | disclosed |
| WO-2009074782-A1 | CANNABINOID RECEPTOR MODULATORS | 7TM PHARMA A/S (DK) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009074782-A1 | CANNABINOID RECEPTOR MODULATORS | 7TM PHARMA A/S (DK) | 2009-06-18 | — | — | WO | disclosed |
| WO-2008074982-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CANNABINOID RECEPTOR | 7TM PHARMA A/S (DK) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292273-A1 | Cannabinoid Receptor Modulators | CNR1, CNR2, CBR1 | NPSR1 63/4885RIPK1 971/4885ALDH1A1 1244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.