Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 18/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679755 | 0.93 | GHSR (0.62) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1787721 | 0.92 | GHSR (0.66) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1787370 | 0.90 | GHSR (0.60) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1787671 | 0.90 | GHSR (0.60) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1785399 | 0.90 | GHSR (0.67) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1784972 | 0.89 | GHSR (0.63) | GHSRCHRNA4SLC6A3HCAR1 | |
| SCHEMBL1788643 | 0.89 | GHSR (0.66) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1788864 | 0.88 | GHSR (0.65) | GHSRCHRNA4SLC6A3HCAR1 | |
| SCHEMBL1789901 | 0.88 | GHSR (0.63) | GHSRMEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL1785425 | 0.88 | GHSR (0.64) | GHSRMEN1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115845-A1 | THERAPEUTIC AGENTS | ALLEN JACK MCQUEEN (GB) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115845-A1 | THERAPEUTIC AGENTS | GPR119, MC2R, MC4R | GHSR 30/4885MEN1 692/4885HPGD 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.