Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 13/20 | 0.66 |
| ▸ | CTSA | P10619 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26470002 | 0.90 | DCAF1 (0.52) | DCAF1CTSAMAPK1 | |
| SCHEMBL26795044 | 0.82 | DCAF1 (0.65) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369820 | 0.79 | DCAF1 (0.63) | DCAF1CTSAMAPK1 | |
| SCHEMBL27278324 | 0.77 | DCAF1 (0.63) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369861 | 0.77 | DCAF1 (0.65) | DCAF1CTSAMAPK1 | |
| SCHEMBL26470124 | 0.74 | DCAF1 (0.59) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369844 | 0.74 | DCAF1 (0.59) | DCAF1CTSAMAPK1 | |
| SCHEMBL27278325 | 0.72 | DCAF1 (0.56) | DCAF1CTSAMAPK1 | |
| SCHEMBL27278326 | 0.72 | DCAF1 (0.58) | DCAF1CTSAMAPK1 | |
| SCHEMBL19025632 | 0.70 | ALDH1A1 (0.56) | DCAF1CTSAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064080-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023220425-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |