Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26795603 | 1.00 | TSHR (0.35) | TSHRNPSR1PTGS2KMT2A | |
| SCHEMBL17937375 | 0.77 | DRD1 (0.33) | PTGS2 | |
| SCHEMBL19829584 | 0.75 | HDAC1 (0.36) | PTGS2 | |
| SCHEMBL26795519 | 0.71 | CA2 (0.41) | TSHRNPSR1PTGS2 | |
| SCHEMBL4127316 | 0.71 | VCAM1 (0.34) | TSHR | |
| SCHEMBL16018018 | 0.70 | TAAR1 (0.48) | KMT2A | |
| SCHEMBL19833060 | 0.70 | CA1 (0.37) | PTGS2 | |
| SCHEMBL27349746 | 0.69 | ESR1 (0.38) | TSHRNPSR1 | |
| SCHEMBL23189364 | 0.69 | RAPGEF4 (0.38) | KMT2A | |
| SCHEMBL17955224 | 0.69 | RAPGEF4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220402-A1 | ENPP1 MODULATORS AND PRODUCTS AND USES THEREOF | GOSSAMER BIO SERVICES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |