Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679660 | 1.00 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2679758 | 0.81 | HDAC3 (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2679766 | 0.81 | HDAC3 (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13352230 | 0.80 | MMP1 (0.64) | ALDH1A1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL10054788 | 0.80 | MAPT (0.59) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10054824 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2679821 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2679819 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL7822330 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL7822334 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426446-B2 | Acrylamide derivative and use thereof in manufacture of medicament | BEIJING SHIQIAO BIOPHARM CO. LTD. (CN) | 2013-04-23 | — | — | US | disclosed |
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | BEIJING JIASHILIANBO PHARM SCI & TECH CO. LTD | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120116075-A1 | Acrylamide Derivative And Use Thereof In Manufacture Of Medicament | ABL1, ABL2, BCR | ALDH1A1 254/4885NPC1 4708/4885RAB9A 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.