Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 3/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26803848 | 0.93 | SIRT6 (0.46) | SIRT6SIRT1TLR2DPP7GNAI3 | |
| SCHEMBL26805124 | 0.93 | SIRT6 (0.48) | SIRT6SIRT1TLR2DPP7GNAI3 | |
| SCHEMBL26804020 | 0.92 | SIRT6 (0.46) | SIRT6SIRT1TLR2DPP7GNAI3 | |
| SCHEMBL26803026 | 0.87 | CA1 (0.40) | SIRT6SIRT1CNR1 | |
| SCHEMBL26864961 | 0.86 | SIRT1 (0.43) | SIRT6SIRT1TLR2MEN1ALDH1A1 | |
| SCHEMBL26864733 | 0.86 | SIRT1 (0.43) | SIRT6SIRT1TLR2MEN1ALDH1A1 | |
| SCHEMBL26864865 | 0.86 | SIRT1 (0.43) | SIRT6SIRT1TLR2MEN1ALDH1A1 | |
| SCHEMBL26803191 | 0.86 | SIRT6 (0.39) | SIRT6SIRT1CNR1 | |
| SCHEMBL26864984 | 0.85 | SIRT1 (0.42) | SIRT6SIRT1TLR2MEN1ALDH1A1 | |
| SCHEMBL26864757 | 0.85 | SIRT1 (0.42) | SIRT6SIRT1TLR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225650-A1 | LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES | OLIX US, INC. (US) | 2023-11-23 | — | — | WO | disclosed |