Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26805281 | 0.87 | HPRT1 (0.42) | LMNASMN1; SMN2GAAPSMB5MAPT | |
| SCHEMBL26805247 | 0.87 | LMNA (0.38) | LMNASMN1; SMN2GAAPSMB5MAPT | |
| SCHEMBL10039115 | 0.83 | HDAC7 (0.46) | LMNAPSMB5MAPTKDM4EALDH1A1 | |
| SCHEMBL11966924 | 0.83 | LMNA (0.41) | LMNASMN1; SMN2GAAPSMB5MAPT | |
| SCHEMBL17734498 | 0.83 | ESR1 (0.38) | LMNASMN1; SMN2GAAMAPTKDM4E | |
| SCHEMBL17734818 | 0.82 | HPRT1 (0.38) | LMNASMN1; SMN2GAAMAPTKDM4E | |
| SCHEMBL9408141 | 0.81 | LMNA (0.38) | LMNASMN1; SMN2GAAPSMB5MAPT | |
| SCHEMBL17734492 | 0.80 | ESR1 (0.40) | LMNASMN1; SMN2GAAPSMB5MAPT | |
| SCHEMBL24432688 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2GAAPSMB5MAPT | |
| SCHEMBL5404983 | 0.79 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115426-A1 | POLYMERS CONTAINING SPIROTRUXENE DERIVATIVES AS THE REPEATING UNITS, AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS | MERCK PATENT GMBH (DE) | 2024-06-06 | — | — | WO | disclosed |
| WO-2023213759-A1 | POLYMERS CONTAINING SPECIALLY SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS | MERCK PATENT GMBH (DE) | 2023-11-09 | — | — | WO | disclosed |