SCHEMBL11966924

SCHEMBL11966924

Cc1ccc(N(c2ccc(-c3ccccc3-c3ccccc3)cc2)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.41
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ GAA P10253 1/20 0.40
▸ PSMB5 P28074 3/20 0.37
▸ MCOLN3 Q8TDD5 1/20 0.36
▸ HDAC7 Q8WUI4 1/20 0.36
▸ HPRT1 P00492 1/20 0.36
▸ RAB9A P51151 3/20 0.35
▸ HTT P42858 1/20 0.35
▸ CA12 O43570 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ CA7 P43166 1/20 0.35
▸ CA9 Q16790 1/20 0.35
▸ CA14 Q9ULX7 1/20 0.35
▸ PTGS2 P35354 1/20 0.35
▸ ESR2 Q92731 1/20 0.35
▸ NPC1 O15118 3/20 0.35
▸ NTSR1 P30989 1/20 0.35
▸ MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16386574 0.89 LMNA (0.38) LMNASMN1; SMN2GAAPSMB5MCOLN3
SCHEMBL14423299 0.88 SMN1; SMN2 (0.41) LMNASMN1; SMN2GAAPSMB5HPRT1
SCHEMBL15946725 0.88 SMN1; SMN2 (0.41) LMNASMN1; SMN2GAAPSMB5HPRT1
SCHEMBL19270237 0.87 ALDH1A1 (0.38) LMNASMN1; SMN2GAAPSMB5RAB9A
SCHEMBL14724014 0.87 RAB9A (0.40) LMNASMN1; SMN2GAAPSMB5HPRT1
SCHEMBL5666518 0.86 ALDH1A1 (0.42) LMNASMN1; SMN2GAAHDAC7RAB9A
SCHEMBL17734498 0.86 ESR1 (0.38) LMNASMN1; SMN2GAAMCOLN3HPRT1
SCHEMBL12388890 0.85 SMN1; SMN2 (0.39) LMNASMN1; SMN2GAAPSMB5HPRT1
SCHEMBL17734818 0.85 HPRT1 (0.38) LMNASMN1; SMN2GAAHPRT1RAB9A
SCHEMBL9408138 0.85 LMNA (0.36) LMNASMN1; SMN2GAAPSMB5MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8241824-B2 Electrophotographic photoreceptor, image forming method, image forming apparatus and process cartridge KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-08-14 — — US disclosed
US-8241824-B2 Electrophotographic photoreceptor, image forming method, image forming apparatus and process cartridge KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-08-14 — — US disclosed
US-20100330480-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-12-30 — — US disclosed
US-20100330480-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-12-30 — — US disclosed
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