SCHEMBL26807117

SCHEMBL26807117

CC(C)(C)c1ccc(CCO[Si](C)(C)C(C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.42
SIGMAR1 Q99720 5/20 0.40
MITF O75030 1/20 0.39
GRIA4 P48058 1/20 0.37
APP P05067 1/20 0.37
SLC13A5 Q86YT5 2/20 0.36
ESRRG P62508 2/20 0.36
DAO P14920 1/20 0.36
DUT P33316 2/20 0.36
ESRRB O95718 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23355637 0.86 DUT (0.35) KCNH2SLC13A5DUT
SCHEMBL2696466 0.84 CYP1A2 (0.41) KCNH2DUT
SCHEMBL19972665 0.82 RORC (0.34) DUT
SCHEMBL2142371 0.82 PPARA (0.42) DUT
SCHEMBL21178368 0.82 DUT (0.36) DUT
SCHEMBL2821530 0.82 ESR1 (0.45) SIGMAR1
SCHEMBL24197444 0.82 TAAR1 (0.44)
SCHEMBL1245973 0.82 ELOVL1 (0.41) KCNH2SIGMAR1DUT
SCHEMBL5871377 0.82 MEN1 (0.42) DUT
SCHEMBL2366928 0.82 GFER (0.45) ESRRGDUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814452-B2 Aziridine polymers whose chemical structural changes are induced by mechanical force KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2023-11-14 US disclosed