SCHEMBL2681685

SCHEMBL2681685

Oc1c(Cl)cncc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9880642 0.81
SCHEMBL16235382 0.81
SCHEMBL16248187 0.75 GABRA1 (0.45)
SCHEMBL4359807 0.72 GPR35 (0.52)
SCHEMBL337576 0.72
SCHEMBL28053348 0.71 IDO1 (0.32)
SCHEMBL15108814 0.69
SCHEMBL4659931 0.69
SCHEMBL18189390 0.69
SCHEMBL3259977 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12084457-B2 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds UNION therapeutics A/S (DK) 2024-09-10 US claimed
CN-118344381-A Process for preparing 1, 3-benzodioxole heterocyclic compounds 联合疗法公司 2024-07-16 CN claimed
CN-114105865-A Synthesis process of 3,4, 5-trichloropyridine 江苏宝众宝达药业股份有限公司 2022-03-01 CN claimed
EP-3642210-B1 METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS UNION THERAPEUTICS AS (DK) 2024-11-13 EP disclosed
US-12084457-B2 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds UNION therapeutics A/S (DK) 2024-09-10 US disclosed
CN-118344381-A Process for preparing 1, 3-benzodioxole heterocyclic compounds 联合疗法公司 2024-07-16 CN disclosed
CN-110741005-B Process for preparing 1, 3-benzodioxole heterocyclic compounds 联合疗法公司 2024-04-12 CN disclosed
US-20220162227-A1 METHODS FOR THE PREPARATION OF 1,3-BENZODIOXOLE HETEROCYCLIC COMPOUNDS UNION therapeutics A/S (DK) 2022-05-26 US disclosed
CN-114105865-A Synthesis process of 3,4, 5-trichloropyridine 江苏宝众宝达药业股份有限公司 2022-03-01 CN disclosed
CN-114105865-A Synthesis process of 3,4, 5-trichloropyridine 江苏宝众宝达药业股份有限公司 2022-03-01 CN disclosed
US-11220514-B2 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds UNION therapeutics A/S (DK) 2022-01-11 US disclosed
EP-1824843-A2 INHIBITORS OF PROTEIN KINASES Locus Pharmaceuticals, Inc. (US) 2007-08-29 EP disclosed
US-20070185098-A1 Inhibitors of protein kinases LOCUS PHARMACEUTICALS, INC. (US) 2007-08-09 US disclosed
WO-2007081690-A2 INHIBITORS OF PROTEIN KINASES LOCUS PHARMACEUTICALS, INC. (US) 2007-07-19 WO disclosed
WO-2006062984-A2 INHIBITORS OF PROTEIN KINASES LOCUS PHARMACEUTICALS, INC. (US) 2006-06-15 WO disclosed
EP-0676397-B1 Oxopyridinylquinoxaline derivatives SHIONOGI & CO (JP) 1999-10-20 EP disclosed
US-5677305-A NERVOUS SYSTEM DISORDERS SHIONOGI & CO., LTD. (JP) 1997-10-14 US disclosed
EP-0676397-A1 Oxopyridinylquinoxaline derivatives SHIONOGI & CO., LTD. (JP) 1995-10-11 EP disclosed
EP-0427549-A1 Heterocyclic oxy-phenoxyacetic acid derivatives and their use as herbicides SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1991-05-15 EP disclosed
US-4173638-A N-Benzoyl-N'-pyridyloxy phenyl urea and insecticidal compositions thereof ISHIHARA SANGYO KAISHA LTD. (JP) 1979-11-06 US disclosed