SCHEMBL28053348

SCHEMBL28053348

Oc1c(Cl)cncc1-c1c(Cl)c[c]cc1Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2681685 0.71
SCHEMBL315854 0.66
SCHEMBL16235382 0.61
SCHEMBL9880642 0.61
SCHEMBL8982961 0.60
SCHEMBL29256316 0.60 CYP1A2 (0.41)
SCHEMBL28075335 0.59 CYP2A6 (0.45)
SCHEMBL28440693 0.58 AKR1C2 (0.52)
SCHEMBL444678 0.58
SCHEMBL16248187 0.57 GABRA1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377837-A N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors ACTIVE BIOTECH AB 2016-03-02 CN disclosed