Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 2/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160203 | 0.84 | TDP1 (0.61) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL2882482 | 0.83 | TDP1 (0.59) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL1038315 | 0.83 | KDM4E (0.69) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL7732690 | 0.83 | TDP1 (0.59) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL8017568 | 0.80 | TDP1 (0.56) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL3862944 | 0.80 | TDP1 (0.70) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL30038122 | 0.80 | TDP1 (0.70) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL11498670 | 0.79 | KDM4E (0.56) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| SCHEMBL1035783 | 0.77 | EGLN3 (0.71) | KDM4ENPC1TDP1CYP11B1CYP11B2 | |
| Hydrogen Sulfide SCHEMBL28767930 | 0.76 | EGLN3 (0.69) | KDM4ENPC1TDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | Changzhou University (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382946-A1 | POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING | PTMS, CBS, CHAMP1 | KDM4E 4700/4885NPC1 4725/4885TDP1 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.