Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366127 | 0.87 | MEN1 (0.49) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL30899639 | 0.87 | MEN1 (0.49) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL12211468 | 0.86 | MEN1 (0.48) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL1464028 | 0.86 | KDM4E (0.48) | MAPTKDM4ETHRBGPR119TP53 | |
| SCHEMBL2680241 | 0.81 | KDM4E (0.48) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL1726323 | 0.81 | KDM4E (0.48) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL13671319 | 0.81 | KDM4E (0.50) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL31736852 | 0.80 | GPR119 (0.57) | MEN1KMT2ANPSR1USP2HPGD | |
| SCHEMBL15167906 | 0.80 | MAPT (0.49) | HPGDMAPTKDM4ETHRBGPR119 | |
| SCHEMBL19404917 | 0.80 | USP30 (0.46) | MEN1KMT2ANPSR1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451801-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| US-8586593-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115884-A1 | INSECTICIDAL COMPOUNDS | ACHE, C1R, C5 | MEN1 1859/4885KMT2A 2686/4885NPSR1 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.