Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223917 | 0.84 | HRH3 (0.58) | HRH3MAPTSMN1; SMN2ALDH1A1MAOB | |
| SCHEMBL26815710 | 0.82 | RXRB (0.53) | KDM1ARCOR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4050773 | 0.82 | RAB9A (0.51) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24628742 | 0.81 | KMT2A (0.50) | HRH3RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4060325 | 0.81 | RAB9A (0.50) | HRH3RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL17554395 | 0.81 | HRH3 (0.55) | KDM1ARCOR1HRH3MCHR1RAB9A | |
| SCHEMBL4139903 | 0.79 | HRH3 (0.52) | HRH3MAPTSMN1; SMN2ALDH1A1MAOB | |
| SCHEMBL18611466 | 0.76 | CARM1 (0.49) | HRH3SMN1; SMN2CTSLCTSBCTSS | |
| SCHEMBL1219263 | 0.76 | ALDH1A1 (0.68) | HRH3RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL15382502 | 0.76 | ALDH1A1 (0.53) | HRH3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |