Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060325 | 0.99 | RAB9A (0.50) | RAB9AALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL510213 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDKDM4EPARP10 | |
| SCHEMBL510687 | 0.84 | HPGD (0.56) | ALDH1A1TSHRHPGDKDM4EPARP10 | |
| SCHEMBL4058730 | 0.84 | HPGD (0.56) | ALDH1A1TSHRHPGDKDM4EPARP10 | |
| SCHEMBL3636729 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDSMN1; SMN2LMNA | |
| SCHEMBL11997230 | 0.82 | HRH3 (0.55) | RAB9AALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL4048737 | 0.82 | HRH3 (0.55) | RAB9AALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL23223734 | 0.82 | RAB9A (0.69) | RAB9AALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL11614936 | 0.82 | RAB9A (0.69) | RAB9AALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL4058957 | 0.81 | HRH3 (0.57) | RAB9AALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |