Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 6/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957446 | 0.93 | GPR84 (0.62) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL8957480 | 0.84 | GPR84 (0.48) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL5236426 | 0.83 | GPR84 (0.64) | GPR84AHRCSNK2A1MEN1POLB | |
| SCHEMBL8957501 | 0.80 | GPR84 (0.46) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL13285075 | 0.79 | GPR84 (0.44) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL396029 | 0.78 | GPR84 (0.42) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL30741638 | 0.78 | CFTR (0.47) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL8529327 | 0.78 | CSNK2A1 (0.55) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL29358322 | 0.78 | GPR84 (0.42) | GPR84AHRCFTRCSNK2A1MEN1 | |
| SCHEMBL188052 | 0.78 | GPR84 (1.00) | GPR84AHRCSNK2A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834450-B2 | Compounds having ((3-nitrophenyl)sulfonyl)acetamide as BCL-2 inhibitors | Eil Therapeutics, Inc. (US) | 2023-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11834450-B2 | Compounds having ((3-nitrophenyl)sulfonyl)acetamide as BCL-2 inhibitors | BCL2, BCL2A1, BCL2L1 | GPR84 3965/4885AHR 1609/4885CFTR 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.