Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 11/20 | 0.33 |
| ▸ | CA1 | P00915 | 10/20 | 0.33 |
| ▸ | CA9 | Q16790 | 10/20 | 0.33 |
| ▸ | P4HB | P07237 | 2/20 | 0.33 |
| ▸ | PDIA4 | P13667 | 2/20 | 0.33 |
| ▸ | PDIA3 | P30101 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764411 | 0.87 | CA2 (0.55) | CA2F10LMNACYP2D6THRB | |
| SCHEMBL29709584 | 0.87 | CA2 (0.55) | CA2F10LMNACYP2D6THRB | |
| SCHEMBL1764410 | 0.87 | CA2 (0.55) | CA2F10LMNACYP2D6THRB | |
| SCHEMBL13640512 | 0.82 | CA2 (0.43) | CA2LMNACYP2D6THRBHSD17B10 | |
| SCHEMBL17022272 | 0.80 | CA2 (0.33) | CA2P4HBPDIA4PDIA3 | |
| SCHEMBL17195630 | 0.80 | CA2 (0.33) | CA2P4HBPDIA4PDIA3 | |
| SCHEMBL12015097 | 0.80 | CA2 (0.33) | CA2P4HBPDIA4PDIA3 | |
| SCHEMBL10028968 | 0.78 | CYP2D6 (0.54) | CA2LMNACYP2D6THRBHSD17B10 | |
| SCHEMBL16939977 | 0.78 | CYP2D6 (0.54) | CA2LMNACYP2D6THRBHSD17B10 | |
| SCHEMBL6997925 | 0.78 | CYP2D6 (0.54) | CA2LMNACYP2D6THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827664-B2 | Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway | REATA PHARMACEUTICALS, INC (US) | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827664-B2 | Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway | HSPA2, HSP90AB2P, HSF1 | CA2 3593/4885F10 3753/4885LMNA 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.