Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 12/20 | 0.39 |
| ▸ | CA1 | P00915 | 11/20 | 0.39 |
| ▸ | CA9 | Q16790 | 10/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.38 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022272 | 0.88 | CA2 (0.33) | CA2P4HBPDIA4PDIA3 | |
| SCHEMBL17195630 | 0.88 | CA2 (0.33) | CA2P4HBPDIA4PDIA3 | |
| SCHEMBL12015097 | 0.88 | CA2 (0.33) | CA2P4HBPDIA4PDIA3 | |
| SCHEMBL543668 | 0.86 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10LMNA | |
| SCHEMBL1753653 | 0.86 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10LMNA | |
| SCHEMBL543667 | 0.86 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10LMNA | |
| SCHEMBL12128029 | 0.86 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10LMNA | |
| SCHEMBL16383664 | 0.86 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10LMNA | |
| SCHEMBL5047747 | 0.86 | CA2 (0.55) | CA2CYP2D6THRBHSD17B10LMNA | |
| SCHEMBL26824176 | 0.82 | CA2 (0.42) | CA2CYP2D6THRBHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023316-B2 | Synthesis of 18F-labeled tracers in hydrous organic solvents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20130005956-A1 | Synthesis of 18F-labeled Tracers in Hydrous Organic Solvents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-01-03 | — | — | US | disclosed |
| US-20120283490-A1 | System, Device and Method for Preparing Tracers and Transferring Materials During Radiosynthesis | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283490-A1 | System, Device and Method for Preparing Tracers and Transferring Materials During Radiosynthesis | TERT, VHL, REV1 | CA2 4693/4885CYP2D6 885/4885THRB 1276/4885 |
| US-20130005956-A1 | Synthesis of 18F-labeled Tracers in Hydrous Organic Solvents | SLCO1B1, SLCO4C1, SLCO2B1 | CA2 2094/4885CYP2D6 1097/4885THRB 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.