⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267180 | 0.82 | — | — | |
| SCHEMBL268061 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL28320399 | 0.75 | POLB (0.31) | — | |
| SCHEMBL28441711 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL28319293 | 0.71 | LMNA (0.35) | — | |
| SCHEMBL29038315 | 0.71 | AR (0.30) | — | |
| SCHEMBL17494470 | 0.70 | LMNA (0.34) | — | |
| SCHEMBL28320395 | 0.69 | TDP1 (0.34) | — | |
| SCHEMBL269869 | 0.69 | ERN1 (0.36) | — | |
| SCHEMBL267265 | 0.69 | ERN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115851-A1 | COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-05-10 | — | — | US | disclosed |
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20060217426-A1 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-09-28 | — | — | US | disclosed |