Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018920 | 1.00 | KARS1 (0.55) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL3892013 | 0.86 | PTGS1 (0.45) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL21683296 | 0.83 | CYP3A4 (0.48) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL151741 | 0.81 | KARS1 (0.56) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL151743 | 0.81 | KARS1 (0.56) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL151742 | 0.81 | KARS1 (0.56) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL13570262 | 0.78 | CYP3A4 (0.42) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL15072076 | 0.74 | CYP3A4 (0.41) | KARS1CYP3A4ALOX15MAPTUSP2 | |
| SCHEMBL24575142 | 0.73 | KARS1 (0.49) | KARS1CYP3A4ALOX15MAPTALDH1A1 | |
| Pomiferin A SCHEMBL1210740 | 0.71 | KARS1 (1.00) | KARS1CYP3A4ALOX15MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827915-B2 | Method for production of novel diterpene scaffolds | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827915-B2 | Method for production of novel diterpene scaffolds | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-11-28 | — | — | US | disclosed |