Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018920 | 0.86 | KARS1 (0.55) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL151742 | 0.82 | KARS1 (0.56) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL151741 | 0.82 | KARS1 (0.56) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL151743 | 0.82 | KARS1 (0.56) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL21683296 | 0.79 | CYP3A4 (0.48) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL24575142 | 0.74 | KARS1 (0.49) | PTGS1CYP3A4CYP2C19KARS1ALOX15 | |
| SCHEMBL13570262 | 0.74 | CYP3A4 (0.42) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL20856804 | 0.73 | KARS1 (0.76) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL15072076 | 0.73 | CYP3A4 (0.41) | CYP3A4CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL18290206 | 0.70 | KARS1 (0.66) | CYP3A4CYP2C19MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578854-B1 | INHIBITION OF ROSIN CRYSTALLIZATION | EASTMAN CHEM CO (US) | 2009-01-21 | — | — | EP | claimed |
| EP-0567000-B1 | Dicyclopentadiene alcohol rosin acid derivatives | GOODYEAR TIRE & RUBBER (US) | 1995-10-11 | — | — | EP | claimed |