Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151741 | 0.89 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL151743 | 0.89 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL151742 | 0.89 | KARS1 (0.56) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL3892013 | 0.74 | PTGS1 (0.45) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL26830176 | 0.73 | KARS1 (0.55) | KARS1POLA1ALOX15LMNACYP3A4 | |
| SCHEMBL30018920 | 0.73 | KARS1 (0.55) | KARS1POLA1ALOX15LMNACYP3A4 | |
| SCHEMBL15072076 | 0.72 | CYP3A4 (0.41) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL21683296 | 0.71 | CYP3A4 (0.48) | KARS1ALOX15LMNACYP3A4PDK1 | |
| SCHEMBL9471626 | 0.70 | KARS1 (0.50) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL20077216 | 0.69 | KARS1 (0.52) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019000-A1 | TREATMENT COMPOSITIONS COMPRISING CERTAIN PLANT ROSIN MATERIALS | The Procter & Gamble Company (US) | 2022-06-29 | — | — | EP | disclosed |