Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 3/20 | 0.58 |
| ▸ | FBP1 | P09467 | 2/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184241 | 1.00 | P2RX3 (0.61) | P2RX3TAS1R3TAS1R1DNPH1FBP1 | |
| SCHEMBL4368535 | 0.92 | P2RX3 (0.67) | P2RX3TRPM2SRCP2RY2P2RY1 | |
| SCHEMBL4356525 | 0.92 | P2RX3 (0.67) | P2RX3TRPM2SRCP2RY2P2RY1 | |
| SCHEMBL316942 | 0.91 | P2RX3 (0.57) | P2RX3TAS1R3TAS1R1DNPH1FBP1 | |
| SCHEMBL1532393 | 0.91 | P2RX3 (0.57) | P2RX3TAS1R3TAS1R1DNPH1FBP1 | |
| SCHEMBL24059927 | 0.90 | P2RX3 (0.70) | P2RX3TRPM2SRCP2RY2P2RY1 | |
| SCHEMBL4363134 | 0.90 | P2RX3 (0.70) | P2RX3TRPM2SRCP2RY2P2RY1 | |
| SCHEMBL4356292 | 0.90 | P2RX3 (0.70) | P2RX3TRPM2SRCP2RY2P2RY1 | |
| SCHEMBL4363151 | 0.90 | P2RX3 (0.70) | P2RX3TRPM2SRCP2RY2P2RY1 | |
| SCHEMBL1030880 | 0.90 | P2RX3 (0.56) | P2RX3TAS1R3TAS1R1DNPH1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120114596-A1 | TSLP PROMOTES IMMUNE EVASION AND PERSISTENCE OF VIRUSES | INSTITUT CURIE (FR) | 2012-05-10 | — | — | US | disclosed |
| EP-2391649-A1 | TSLP PROMOTES IMMUNE EVASION AND PERSISTENCE OF VIRUSES | Institut Curie (FR) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086445-A1 | TSLP PROMOTES IMMUNE EVASION AND PERSISTENCE OF VIRUSES | INSTITUT CURIE (FR) | 2010-08-05 | — | — | WO | disclosed |
| EP-2213682-A1 | TSLP promotes immune evasion and persistence of viruses | Institut Curie (FR) | 2010-08-04 | — | — | EP | disclosed |
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |