Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 3/20 | 0.52 |
| ▸ | P2RY1 known ✓ | P47900 | 6/20 | 0.52 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.50 |
| ▸ | IMPDH2 known ✓ | P12268 | 5/20 | 0.48 |
| ▸ | IMPDH1 known ✓ | P20839 | 1/20 | 0.48 |
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.48 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.48 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.52 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.49 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316942 | 1.00 | P2RX3 (0.57) | P2RX3ADORA1P2RY1ENPP1ADORA3 | |
| SCHEMBL1030880 | 0.99 | P2RX3 (0.56) | P2RX3ADORA1P2RY1ENPP1ADORA3 | |
| Water SCHEMBL20266269 | 0.99 | P2RX3 (0.56) | P2RX3ADORA1P2RY1ENPP1ADORA3 | |
| SCHEMBL2683124 | 0.91 | P2RX3 (0.61) | P2RX3ADORA1P2RY1P2RY11IMPDH2 | |
| SCHEMBL184241 | 0.91 | P2RX3 (0.61) | P2RX3ADORA1P2RY1P2RY11IMPDH2 | |
| SCHEMBL4356525 | 0.87 | P2RX3 (0.67) | P2RX3P2RY1ENPP1P2RY11TRPM2 | |
| SCHEMBL4368535 | 0.87 | P2RX3 (0.67) | P2RX3P2RY1ENPP1P2RY11TRPM2 | |
| SCHEMBL24059927 | 0.85 | P2RX3 (0.70) | P2RX3P2RY1ENPP1P2RY11TRPM2 | |
| SCHEMBL4356292 | 0.85 | P2RX3 (0.70) | P2RX3P2RY1ENPP1P2RY11TRPM2 | |
| SCHEMBL4363134 | 0.85 | P2RX3 (0.70) | P2RX3P2RY1ENPP1P2RY11TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630407-A1 | 2-METHYL-2-(1-METHYLCYCLOHEXYL)PROPANAMIDE DERIVATIVES AND 1-(TERT-BUTYL)-CYCLOHEXANE-1-CARBOXAMIDE DERIVATIVES FOR USE IN UMAMI FLAVOR COMPOSITIONS | International Flavors & Fragrances, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| CN-118125875-B | Amino acid-containing water-soluble fertilizer and preparation method thereof | 广州市绿量有机肥料有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118125875-A | Amino acid-containing water-soluble fertilizer and preparation method thereof | 广州市绿量有机肥料有限公司 | 2024-06-04 | — | — | CN | disclosed |
| US-11612575-B2 | Combination therapies with disulfiram | Spring Discovery, Inc. (US) | 2023-03-28 | — | — | US | disclosed |
| US-20220087956-A1 | COMBINATION THERAPIES WITH DISULFIRAM | WINTER ACQUISITION SUB, INC. | 2022-03-24 | — | — | US | disclosed |
| US-20220087955-A1 | COMBINATION THERAPIES WITH DISULFIRAM | WINTER ACQUISITION SUB, INC. | 2022-03-24 | — | — | US | disclosed |
| US-11065214-B1 | Combination therapies with disulfiram | Spring Discovery, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| CN-110074399-A | For promoting the alimentation composition of satiety | MJN 美国控股有限责任公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-106999973-A | System and method for discharging edible material | 阿甘芳香和精细化工有限公司 | 2017-08-01 | — | — | CN | disclosed |
| EP-2292585-B1 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT WEST LAFAYETTE LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-2931064-A1 | NUTRITIONAL COMPOSITION FOR PROMOTING SATIETY | MJN U.S. Holdings, LLC (US) | 2015-10-21 | — | — | EP | disclosed |
| CN-104837368-A | Nutritional composition for promoting satiety | MJN US HOLDINGS LLC | 2015-08-12 | — | — | CN | disclosed |
| US-8920559-B2 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT (WEST LAFAYETTE), LLC (US) | 2014-12-30 | — | — | US | disclosed |
| WO-2014092861-A1 | NUTRITIONAL COMPOSITION FOR PROMOTING SATIETY | MJN U.S. HOLDINGS LLC (US) | 2014-06-19 | — | — | WO | disclosed |
| US-20140170259-A1 | NUTRITIONAL COMPOSITION FOR PROMOTING SATIETY | MEAD JOHNSON NUTRITION COMPANY (US) | 2014-06-19 | — | — | US | disclosed |
| US-20110257430-A1 | NOVEL COCRYSTALLIZATION | APTUIT (KANSAS CITY), LLC (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110251426-A1 | SCREENING FOR SOLID FORMS BY ULTRASOUND CRYSTALLIZATION AND COCRYSTALLIZATION USING ULTRASOUND | S.S.C.I., INC. (US) | 2011-10-13 | — | — | US | disclosed |
| EP-2292585-A1 | Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound | APTUIT (KANSAS CITY), LLC (US) | 2011-03-09 | — | — | EP | disclosed |