Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26833508 | 0.93 | PIK3CD (0.58) | PIK3CDPIK3CAEGFRTDO2KDM4E | |
| SCHEMBL26833563 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CAEGFRTDO2KDM4E | |
| SCHEMBL26833457 | 0.84 | NPC1 (0.47) | KDM4ECYP11B1CYP11B2CYP17A1CYP19A1 | |
| SCHEMBL26833597 | 0.82 | KDM4E (0.44) | PIK3CDPIK3CAKDM4ECYP11B1CYP11B2 | |
| SCHEMBL26833569 | 0.82 | MAPK9 (0.43) | PIK3CDPIK3CAEGFRTDO2KDM4E | |
| SCHEMBL26833455 | 0.82 | PRKCZ (0.50) | PIK3CDTDO2MAPK9MAPK10CYP11B1 | |
| SCHEMBL26833454 | 0.82 | CYP17A1 (0.48) | PIK3CDTDO2MAPK9MAPK10CYP11B1 | |
| SCHEMBL26833448 | 0.82 | PDGFRB (0.50) | PIK3CDPIK3CAPIK3CBMTORPIK3CG | |
| SCHEMBL26424153 | 0.82 | PIK3CD (0.45) | PIK3CDPIK3CAEGFRTDO2KDM4E | |
| SCHEMBL26833501 | 0.81 | NPC1 (0.44) | PIK3CDPIK3CACYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | AHR, ORAI3, WNT3 | PIK3CD 3986/4885PIK3CA 2980/4885EGFR 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.