Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26833540 | 0.92 | CYP17A1 (0.41) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833461 | 0.90 | HTR2B (0.42) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833626 | 0.87 | HTR2B (0.44) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833455 | 0.85 | PRKCZ (0.50) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833454 | 0.85 | CYP17A1 (0.48) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833649 | 0.85 | CYP17A1 (0.41) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833469 | 0.85 | TNF (0.55) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833571 | 0.85 | HTR2B (0.40) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833663 | 0.84 | MAPK10 (0.43) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 | |
| SCHEMBL26833521 | 0.82 | PDGFRB (0.48) | CYP17A1CYP19A1CYP11B1CYP11B2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357188-A1 | PHENANTHRENE ORGANIC COMPOUND AND USE THEREOF | AHR, ORAI3, WNT3 | CYP17A1 560/4885CYP19A1 318/4885CYP11B1 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.