Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 16/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 16/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 16/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.42 |
| ▸ | TSHR | P16473 | 12/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087225 | 0.92 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL2683612 | 0.90 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL10087226 | 0.84 | CTNNB1 (0.41) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2684380 | 0.82 | ADORA3 (0.35) | CYP1A2CYP3A4CYP2C19HSD17B10LMNA | |
| SCHEMBL10087222 | 0.82 | HSP90AA1 (0.36) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL2684322 | 0.82 | HTT (0.40) | CYP1A2CYP3A4CYP2C19CYP2D6LMNA | |
| SCHEMBL10087223 | 0.81 | ALDH1A1 (0.37) | TSHRHSD17B10LMNASMN1; SMN2MAPT | |
| SCHEMBL11902944 | 0.80 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL2684115 | 0.79 | JAK3 (0.33) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11902580 | 0.79 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115724-A1 | METHOD OF CONTROLLING UNDESIRED VEGETATION | TYMS, DHFR, UNG | CYP1A2 860/4885CYP3A4 2326/4885CYP2C19 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.