SCHEMBL26846799

SCHEMBL26846799

[N-]=[N+]=NCCOCCOCCOCCNCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 3/20 0.36
▸ TTR P02766 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14713434 0.93 CRBN (0.33) CRBN
SCHEMBL29444978 0.93 CRBN (0.33) CRBN
SCHEMBL29521618 0.93 CRBN (0.33) CRBN
SCHEMBL17319197 0.93 CRBN (0.33) CRBN
SCHEMBL19725973 0.93 CRBN (0.33) CRBN
SCHEMBL23194379 0.93 CRBN (0.33) CRBN
SCHEMBL14981499 0.93 CRBN (0.33) CRBN
SCHEMBL16329452 0.93 CRBN (0.33) CRBN
SCHEMBL22657962 0.93 CRBN (0.33) CRBN
SCHEMBL16329449 0.91 GAA (0.33) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364262-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230364262-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES FCGR1A, FCGR3B, FCGR2A CRBN 406/4885TTR 4841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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