SCHEMBL14713434

SCHEMBL14713434

[N-]=[N+]=NCCOCCOCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 3/20 0.33
▸ MGMT P16455 1/20 0.33
▸ GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22657962 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL29444978 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL29521618 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL17319197 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL19725973 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL23194379 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL14981499 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL16329452 1.00 CRBN (0.33) CRBNMGMTGAA
SCHEMBL16329449 0.99 GAA (0.33) CRBNMGMTGAA
SCHEMBL26846799 0.93 CRBN (0.36) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 — — US disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-11819531-B2 Multifunctional zwitterionic polymer conjugates KODIAK SCIENCES INC. (US) 2023-11-21 — — US disclosed
US-11819531-B2 Multifunctional zwitterionic polymer conjugates KODIAK SCIENCES INC. (US) 2023-11-21 — — US disclosed
EP-4274582-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS Osprey Biopharmaceuticals, Inc. (US) 2023-11-15 — — EP disclosed
EP-3659591-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2023-10-25 — — EP disclosed
US-11779663-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-10-10 — — US disclosed
US-11779663-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-10-10 — — US disclosed
CN-116744944-A Low-immunogenicity biotherapeutic medicine 奥斯普瑞生物制药有限公司 2023-09-12 — — CN disclosed
US-20170002013-A1 SUBSTITUTED 4-METHYL-PYRROLO[1,2-A]PYRIMIDINE-8-CARBOXAMIDE COMPOUNDS AND USES THEREOF FOR MODULATING GLUCOCEREBROSIDASE ACTIVITY NORTHWESTERN UNIVERSITY (US) 2017-01-05 — — US disclosed
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2016-10-06 — — US disclosed
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2016-10-06 — — US disclosed
WO-2015179823-A2 LUNG LOCALIZED INHIBITORS OF ALPHA(V)BETA 6 THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2015-11-26 — — WO disclosed
US-8734846-B2 Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles BIND BIOSCIENCES, INC. (US) 2014-05-27 — — US disclosed
US-20130115192-A1 Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles BIND BIOSCIENCES, INC (US) 2013-05-09 — — US disclosed
US-20130045522-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2013-02-21 — — US disclosed
US-20130045522-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2013-02-21 — — US disclosed
WO-2011075736-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 — — WO disclosed
US-20100104645-A1 METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES BIND BIOSCIENCES, INC. (US) 2010-04-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 CRBN 1913/4885MGMT 1221/4885GAA 1525/4885
US-20130115192-A1 Methods for the Preparation of Targeting Agent Functionalized Diblock Copolymers for Use in Fabrication of Therapeutic Targeted Nanoparticles GNE, PAM, EPHA2 CRBN 299/4885MGMT 383/4885GAA 271/4885
US-20170002013-A1 SUBSTITUTED 4-METHYL-PYRROLO[1,2-A]PYRIMIDINE-8-CARBOXAMIDE COMPOUNDS AND USES THEREOF FOR MODULATING GLUCOCEREBROSIDASE ACTIVITY GBA1, GBA2, GBA3 CRBN 3586/4885MGMT 3550/4885GAA 5/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 CRBN 3368/4885MGMT 3249/4885GAA 2425/4885
US-11779663-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof SLC25A1, GCDH, FH CRBN 3796/4885MGMT 820/4885GAA 2416/4885
US-11819531-B2 Multifunctional zwitterionic polymer conjugates PHOSPHO1, MSN, ZW10 CRBN 1913/4885MGMT 1221/4885GAA 1525/4885
US-20100104645-A1 METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC TARGETED NANOPARTICLES GNE, EPHA2, PAM CRBN 839/4885MGMT 1047/4885GAA 96/4885
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 CRBN 642/4885MGMT 3238/4885GAA 1416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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