Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.36 |
| ▸ | KDM6B | O15054 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26850357 | 0.87 | KDM4C (0.44) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL30716135 | 0.87 | KDM4C (0.44) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL30716134 | 0.87 | KDM4C (0.44) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL26850328 | 0.75 | TDP1 (0.34) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL4582070 | 0.69 | KDM4C (0.50) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL26850334 | 0.69 | TDP1 (0.34) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL26841347 | 0.69 | TBXAS1 (0.38) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| Hydrochloric Acid SCHEMBL5740286 | 0.68 | KDM4C (0.49) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL20462852 | 0.67 | KDM4C (0.46) | TDP1SIRT3KDM4CKDM6BKDM4E | |
| SCHEMBL14081784 | 0.66 | TDP1 (0.57) | TDP1SIRT3KDM4CKDM6BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372323-A1 | Nicotinic Acid Derivative A With Anti-Inflammation and Anti-Platelet Aggregation Activities, and Use Thereof | CHONGQING ACADEMY OF CHINESE MATERIA MEDICA (CN) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372323-A1 | Nicotinic Acid Derivative A With Anti-Inflammation and Anti-Platelet Aggregation Activities, and Use Thereof | NAPRT, P2RY1, P2RY10 | TDP1 1477/4885SIRT3 400/4885KDM4C 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.