Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.50 |
| ▸ | KDM6B | O15054 | 5/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5740286 | 0.98 | KDM4C (0.49) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL20462852 | 0.85 | KDM4C (0.46) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL17465921 | 0.85 | KDM4C (0.53) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL3818665 | 0.85 | SIRT3 (0.43) | KDM4CKDM6BTDP1ALDH1A1TGFBR1 | |
| SCHEMBL6215853 | 0.83 | SIRT3 (0.59) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL30716135 | 0.82 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL26850357 | 0.82 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL20053816 | 0.82 | KDM4C (0.48) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL30716134 | 0.82 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL30010471 | 0.82 | KDM4C (0.46) | KDM4CKDM6BKDM4DTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008049651-A1 | PERFORMANCE-ENHANCED COSMETIC COMPOSITIONS WITH PURINE AND/OR PURINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2008-05-02 | — | — | WO | claimed |
| EP-1880705-A2 | Brightening and/or colouring composition with improved product sensation | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1842573-A2 | Brightening and/or colouring agent with improved product sensation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-10-10 | — | — | EP | claimed |
| EP-1633334-B1 | TOPICAL ADMINISTRATION OF VASOACTIVE VITAMIN B3 COMPOUNDS FOR PROMOTING SLEEP | PROCTER & GAMBLE (US) | 2006-11-15 | — | — | EP | claimed |
| US-20210363155-A1 | 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-11-25 | — | — | US | disclosed |
| US-11028098-B2 | 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-06-08 | — | — | US | disclosed |
| US-10570148-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-02-25 | — | — | US | disclosed |
| US-10421720-B2 | Octahydrocyclopentapyrroles, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-09-24 | — | — | US | disclosed |
| US-10273243-B2 | 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-04-30 | — | — | US | disclosed |
| US-20190031681-A1 | 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-01-31 | — | — | US | disclosed |
| US-20180222919-A1 | N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-08-09 | — | — | US | disclosed |
| US-9951075-B2 | Pteridines useful as HCV inhibitors and methods for the preparation thereof | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-24 | — | — | US | disclosed |
| EP-1684754-A1 | HMG-COA REDUCTASE INHIBITORS AND METHOD | Bristol-Myers Squibb Company (US) | 2006-08-02 | — | — | EP | disclosed |
| EP-1678138-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | Takeda Pharmaceutical Company Limited (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005051386-A1 | HMG-COA REDUCTASE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005042488-A1 | PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-20040209924-A1 | Substituted 3-pyridyl imidazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-10-21 | — | — | US | disclosed |
| US-20040198773-A1 | Substituted 3-pyridyl oxazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-10-07 | — | — | US | disclosed |
| WO-2003027107-A1 | SUBSTITUTED 3-PYRIDYL OXAZOLES AS C17,20 LYASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003027096-A1 | SUBSTITUTED 3-PYRIDYL IMIDAZOLES AS C17,20 LYASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273243-B2 | 4-phenylpiperidines, their preparation and use | HTR3C, HRH4, CYP4F3 | KDM4C 403/4885KDM6B 2843/4885KDM4D 656/4885 |
| US-10570148-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | HRH3, CBR3, KCNH3 | KDM4C 226/4885KDM6B 1762/4885KDM4D 952/4885 |
| US-20210363155-A1 | 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HTR3C, HRH4, CYP4F3 | KDM4C 452/4885KDM6B 2984/4885KDM4D 729/4885 |
| US-11028098-B2 | 4-phenylpiperidines, their preparation and use | HTR3C, HRH4, CYP4F3 | KDM4C 365/4885KDM6B 2825/4885KDM4D 586/4885 |
| US-20190031681-A1 | 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HTR3C, HRH4, CYP4F3 | KDM4C 365/4885KDM6B 2825/4885KDM4D 586/4885 |
| US-10421720-B2 | Octahydrocyclopentapyrroles, their preparation and use | CLN6, ALDH1A2, C1S | KDM4C 3968/4885KDM6B 4246/4885KDM4D 4527/4885 |
| US-20180222919-A1 | N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE | HRH3, CBR3, KCNH3 | KDM4C 226/4885KDM6B 1762/4885KDM4D 952/4885 |
| US-20040198773-A1 | Substituted 3-pyridyl oxazoles as c17,20 lyase inhibitors | CYP17A1, HSD17B12, DCLRE1B | KDM4C 442/4885KDM6B 642/4885KDM4D 2297/4885 |
| US-20040209924-A1 | Substituted 3-pyridyl imidazoles as c17,20 lyase inhibitors | CDC20, IDH1, ALDH18A1 | KDM4C 168/4885KDM6B 92/4885KDM4D 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.