Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.44 |
| ▸ | KDM6B | O15054 | 6/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716135 | 1.00 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL30716134 | 1.00 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL26850305 | 0.87 | TDP1 (0.37) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL4582070 | 0.82 | KDM4C (0.50) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL5740286 | 0.81 | KDM4C (0.49) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL20462852 | 0.79 | KDM4C (0.46) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL20053816 | 0.77 | KDM4C (0.48) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL3932429 | 0.75 | KDM4C (0.48) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL30716132 | 0.73 | KDM4C (0.41) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL30716141 | 0.73 | KDM4C (0.41) | KDM4CKDM6BKDM4DTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117637186-A | Method for screening and preparing active molecule group in tripterygium plants and application thereof | 重庆市中药研究院 | 2024-03-01 | — | — | CN | claimed |
| CN-117338831-A | Low-toxicity tripterygium wilfordii extract and preparation method and application thereof | 重庆市中药研究院 | 2024-01-05 | — | — | CN | claimed |
| US-20230372323-A1 | Nicotinic Acid Derivative A With Anti-Inflammation and Anti-Platelet Aggregation Activities, and Use Thereof | CHONGQING ACADEMY OF CHINESE MATERIA MEDICA (CN) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372323-A1 | Nicotinic Acid Derivative A With Anti-Inflammation and Anti-Platelet Aggregation Activities, and Use Thereof | NAPRT, P2RY1, P2RY10 | KDM4C 4816/4885KDM6B 4159/4885KDM4D 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.