Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327562 | 0.77 | TDP1 (0.54) | L3MBTL1ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL12330301 | 0.75 | NPC1 (0.70) | L3MBTL1ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL27425744 | 0.72 | NPC1 (0.58) | ALDH1A1KDM4ETDP1RAB9ANPC1 | |
| SCHEMBL13853886 | 0.71 | KDM4E (0.54) | L3MBTL1KDM4ETDP1RAB9ANPC1 | |
| SCHEMBL12506243 | 0.70 | TDP1 (0.59) | L3MBTL1ALDH1A1TDP1RAB9ANPC1 | |
| SCHEMBL3022199 | 0.70 | TDP1 (0.59) | L3MBTL1ALDH1A1TDP1RAB9ANPC1 | |
| SCHEMBL24834896 | 0.70 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL12500555 | 0.70 | CTSL (0.53) | ALDH1A1KDM4EMAPTCTSLLMNA | |
| Benzylacetone SCHEMBL28182445 | 0.69 | ALDH1A1 (0.81) | L3MBTL1ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL20662962 | 0.69 | KMT2A (0.45) | L3MBTL1ALDH1A1KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225327-A1 | INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-11-23 | — | — | WO | disclosed |