Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26853629 | 1.00 | TBXAS1 (0.33) | TBXAS1SMPD1SLC9A1PTGS1PTGS2 | |
| SCHEMBL22951453 | 0.80 | — | — | |
| SCHEMBL22211249 | 0.77 | LRRK2 (0.30) | — | |
| SCHEMBL26849593 | 0.75 | CNR2 (0.33) | SMPD1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL26850283 | 0.75 | CNR2 (0.33) | SMPD1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL25101264 | 0.75 | TLR8 (0.40) | TBXAS1KMT2A | |
| SCHEMBL22388573 | 0.75 | TLR8 (0.40) | TBXAS1KMT2A | |
| SCHEMBL20047667 | 0.75 | TLR8 (0.40) | TBXAS1KMT2A | |
| SCHEMBL21719521 | 0.73 | CNR2 (0.32) | TBXAS1CNR2KMT2A | |
| SCHEMBL22955757 | 0.72 | ALDH1A1 (0.32) | SMPD1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | TRPV1, SCN3A, KCNN3 | TBXAS1 646/4885SMPD1 1632/4885SLC9A1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.