Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396439 | 1.00 | DRD2 (0.49) | DRD2DRD3DRD1DRD5CYP2A6 | |
| SCHEMBL2061100 | 0.91 | DRD2 (0.47) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL2061271 | 0.87 | DRD2 (0.50) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL266381 | 0.86 | DRD2 (0.55) | DRD2DRD3DRD1DRD5CYP2A6 | |
| SCHEMBL2641069 | 0.85 | DRD2 (0.50) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL4602431 | 0.81 | CYP2A6 (0.43) | CYP2A6KDM4EALDH1A1GAA | |
| SCHEMBL4601170 | 0.81 | CYP2A6 (0.43) | DRD2DRD3CYP2A6ALDH1A1ACHE | |
| SCHEMBL2061606 | 0.81 | DRD2 (0.54) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL19133719 | 0.81 | DRD2 (0.58) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL4360295 | 0.80 | CYP2A6 (0.42) | DRD2DRD1CYP2A6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977826-A | Rotigotine intermediate and preparation method and application thereof | 烟台药物研究所 | 2025-05-13 | — | — | CN | claimed |
| CN-119753049-A | Preparation method of rotigotine | 滁州市庆云医药有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-118956991-B | Synthesis method of chiral amine | 天津凯莱英生物科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-118460498-B | High-activity heat-resistant aminotransferase mutant and encoding gene, construction method and application thereof | 中国科学院苏州生物医学工程技术研究所 | 2025-01-24 | — | — | CN | claimed |
| CN-119143720-A | Rotigotine is got Process for the preparation of a statin | 诚弘制药(威海)有限责任公司 | 2024-12-17 | — | — | CN | claimed |
| CN-118956991-A | Synthesis method of chiral amine | 天津凯莱英生物科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118460498-A | High-activity heat-resistant aminotransferase mutant and encoding gene, construction method and application thereof | 中国科学院苏州生物医学工程技术研究所 | 2024-08-09 | — | — | CN | claimed |
| CN-114276258-B | Novel chiral tetrahydronaphthylamine compound, and preparation method and application thereof | 四川青木制药有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117965476-A | Reductive amination enzyme mutant and application thereof in rotigotine molecular synthesis | 中国科学院天津工业生物技术研究所 | 2024-05-03 | — | — | CN | claimed |
| CN-116621775-A | 2-amino-5-hydroxytetrahydronaphthalene derivative containing hydroxypyridone side chain, preparation and application thereof | 浙江大学 | 2023-08-22 | — | — | CN | claimed |
| EP-2684953-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | Kaneka Corporation (JP) | 2014-01-15 | — | — | EP | claimed |
| US-20140004575-A1 | MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME | KANEKA CORPORATION (JP) | 2014-01-02 | — | — | US | claimed |
| US-20130210092-A1 | Novel Transaminase, Gene Encoding the Same, and Method Using Them | KANEKA CORPORATION (JP) | 2013-08-15 | — | — | US | claimed |
| EP-2623593-A1 | NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| EP-2623595-A1 | NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF | Kaneka Corporation (JP) | 2013-08-07 | — | — | EP | claimed |
| US-20130196389-A1 | NOVEL TRANSAMINASE EXHIBITING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR USING THEM | KANEKA CORPORATION (JP) | 2013-08-01 | — | — | US | claimed |
| EP-2531486-A2 | NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES | UCB Pharma GmbH (DE) | 2012-12-12 | — | — | EP | claimed |
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | UCB PHARMA, S.A. (BE) | 2012-11-29 | — | — | US | claimed |
| WO-2011095539-A2 | NOVEL PROCESS FOR THE PREPARATION OF NITROGEN SUBSTITUTED AMINOTETRALINS DERIVATIVES | UCB PHARMA GMBH (DE) | 2011-08-11 | — | — | WO | claimed |
| EP-1889907-A1 | NOVEL AMINO GROUP TRANSFERASE, GENE ENCODING THE SAME AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2008-02-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302790-A1 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives | AADAT, AANAT, ASNS | DRD2 572/4885DRD3 919/4885DRD1 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.