Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | INMT | O95050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719930 | 0.98 | MAPT (0.49) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL10047902 | 0.85 | MAPT (0.48) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL19543208 | 0.81 | ALDH1A1 (0.51) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL19543209 | 0.81 | MAPT (0.45) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL19543207 | 0.81 | KMT2A (0.45) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL10038918 | 0.81 | KMT2A (0.49) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL2683601 | 0.80 | MAPT (0.46) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL13748501 | 0.80 | MAPT (0.47) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL18476008 | 0.80 | MAPT (0.46) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL21743130 | 0.80 | MAPT (0.46) | MAPTKMT2AALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119465117-A | Application of thiazole thioketone compound in electroless copper plating and electroless copper plating solution | 广东东硕科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119465117-A | Application of thiazole thioketone compound in electroless copper plating and electroless copper plating solution | 广东东硕科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-20140039158-A1 | POLYMERIC CONJUGATES AND METHODS OF PREPARING THE SAME | BELROSE PHARMA, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140039158-A1 | POLYMERIC CONJUGATES AND METHODS OF PREPARING THE SAME | BELROSE PHARMA, INC. (US) | 2014-02-06 | — | — | US | disclosed |
| US-8168647-B2 | Vinblastine derivatives, their preparation, use and pharmaceutical compositions comprising the said derivatives | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2012-05-01 | — | — | US | disclosed |
| US-8168647-B2 | Vinblastine derivatives, their preparation, use and pharmaceutical compositions comprising the said derivatives | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2012-05-01 | — | — | US | disclosed |
| US-8168647-B2 | Vinblastine derivatives, their preparation, use and pharmaceutical compositions comprising the said derivatives | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2012-05-01 | — | — | US | disclosed |
| US-20100113498-A1 | NOVEL VINBLASTINE DERIVATIVES, THEIR PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAID DERIVATIVES | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113498-A1 | NOVEL VINBLASTINE DERIVATIVES, THEIR PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAID DERIVATIVES | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-05-06 | — | — | US | disclosed |
| US-20100113498-A1 | NOVEL VINBLASTINE DERIVATIVES, THEIR PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAID DERIVATIVES | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-05-06 | — | — | US | disclosed |
| US-4990613-A | Bactericides | LEDERLE (JAPAN), LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0289801-B1 | (1R,5S,6S)-2-(substituted thio)-6-[(R)-1-hydroxy-ethyl]-1-methyl-carbapenem-3-carboxylic-acid derivatives | LEDERLE (JAPAN) LTD. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4925836-A | NONTOXIC, SIDE EFFECT REDUCTION | LEDERLE (JAPAN), LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4925935-A | BACTERICIDES | LEDERLE (JAPAN), LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4918184-A | REACTING 1,3-THIAZOLIDINE-2-THIONE DERIVATIVE WITH TIN TRIFLUOROMETHANESULFONATE TO FORM ENOLATE, REACTING WITH SUBSTITUTED AZETIDINONE | LEDERLE (JAPAN), LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4866171-A | THIENAMYCIN ANTIBIOTIC | LEDERLE (JAPAN), LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0326640-A1 | (1R,5S,6S)-2-substituted thio-6 (R)-1-hydroxyethyl -1-methyl-carbapenem - carboxylic acid derivatives | LEDERLE (JAPAN) LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| EP-0289801-A1 | (1R,5S,6S)-2-(substituted thio)-6-[(R)-1-hydroxy-ethyl]-1-methyl-carbapenem-3-carboxylic-acid derivatives | LEDERLE (JAPAN) LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0239853-A1 | 3,4-Disubstituted-2-azetidinone derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0213610-A1 | Azetidin-2-one derivatives and process for production thereof | LEDERLE (JAPAN) LTD. (JP) | 1987-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039158-A1 | POLYMERIC CONJUGATES AND METHODS OF PREPARING THE SAME | PHYKPL, LNPEP, DNPEP | MAPT 916/4885KMT2A 770/4885ALDH1A1 4220/4885 |
| US-20100113498-A1 | NOVEL VINBLASTINE DERIVATIVES, THEIR PREPARATION, USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAID DERIVATIVES | MCL1, BAX, BAD | MAPT 1180/4885KMT2A 673/4885ALDH1A1 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.