Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855091 | 0.87 | APAF1 (0.46) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26855827 | 0.87 | APAF1 (0.63) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26855991 | 0.80 | KMT2A (0.54) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26855601 | 0.78 | IDO1 (0.48) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26855341 | 0.76 | MEN1 (0.43) | APAF1IDO1EGFRPOLBKMT2A | |
| SCHEMBL30639108 | 0.74 | IDO1 (0.63) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26614117 | 0.74 | IDO1 (0.63) | APAF1IDO1TDO2IDO2KMT2A | |
| SCHEMBL26614091 | 0.72 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639072 | 0.71 | APAF1 (0.62) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL20597470 | 0.71 | IDO1 (0.73) | APAF1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |