Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855588 | 0.90 | POLB (0.44) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL26614146 | 0.89 | APAF1 (0.53) | MEN1KMT2ACYP1A2TSHRNFKB1 | |
| SCHEMBL26855589 | 0.86 | POLB (0.41) | MEN1KMT2AAPAF1POLBEGFR | |
| SCHEMBL26614232 | 0.81 | APAF1 (0.57) | MEN1KMT2AAPAF1POLBEGFR | |
| SCHEMBL26614211 | 0.79 | APAF1 (0.50) | MEN1KMT2AAPAF1POLBEGFR | |
| SCHEMBL30639057 | 0.79 | APAF1 (0.50) | MEN1KMT2AAPAF1POLBEGFR | |
| SCHEMBL26855333 | 0.78 | POLB (0.41) | MEN1KMT2AAPAF1POLBEGFR | |
| SCHEMBL26862920 | 0.78 | IDO1 (0.53) | MEN1KMT2ATERTAPAF1IDO1 | |
| Hydrochloric Acid SCHEMBL26614186 | 0.77 | IDO1 (0.53) | MEN1KMT2ATERTAPAF1IDO1 | |
| SCHEMBL26855335 | 0.76 | APAF1 (0.48) | MEN1KMT2AAPAF1POLBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |