Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855333 | 0.92 | POLB (0.41) | POLBBRD4KMT2AMEN1EGFR | |
| SCHEMBL30639088 | 0.90 | APAF1 (0.48) | POLBBRD4KMT2AMEN1EGFR | |
| SCHEMBL26855829 | 0.90 | APAF1 (0.48) | POLBBRD4KMT2AMEN1EGFR | |
| SCHEMBL26855341 | 0.86 | MEN1 (0.43) | POLBKMT2AMEN1EGFRAPAF1 | |
| SCHEMBL30639128 | 0.80 | IDO1 (0.50) | KMT2AMEN1APAF1 | |
| SCHEMBL26855588 | 0.80 | POLB (0.44) | POLBKMT2AMEN1EGFRAPAF1 | |
| SCHEMBL30639054 | 0.78 | APAF1 (0.39) | BRD4KMT2AMEN1APAF1 | |
| SCHEMBL26614232 | 0.78 | APAF1 (0.57) | POLBKMT2AMEN1EGFRAPAF1 | |
| SCHEMBL30639106 | 0.75 | APAF1 (0.48) | EGFRAPAF1 | |
| SCHEMBL26860163 | 0.75 | APAF1 (0.48) | EGFRAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |