Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26855341 | 0.90 | MEN1 (0.43) | POLBMEN1KMT2AIDO1EGFR | |
| SCHEMBL26855333 | 0.88 | POLB (0.41) | POLBMEN1KMT2AIDO1EGFR | |
| SCHEMBL26614146 | 0.86 | APAF1 (0.53) | MEN1KMT2AIDO1EGFRCYP1A2 | |
| SCHEMBL26855589 | 0.80 | POLB (0.41) | POLBMEN1KMT2AEGFRAPAF1 | |
| SCHEMBL26614232 | 0.78 | APAF1 (0.57) | POLBMEN1KMT2AIDO1EGFR | |
| SCHEMBL26855091 | 0.77 | APAF1 (0.46) | POLBMEN1KMT2AIDO1EGFR | |
| SCHEMBL26855331 | 0.76 | KMT2A (0.49) | MEN1KMT2AIDO1EGFRAPAF1 | |
| SCHEMBL30639057 | 0.76 | APAF1 (0.50) | POLBMEN1KMT2AIDO1EGFR | |
| SCHEMBL26614211 | 0.76 | APAF1 (0.50) | POLBMEN1KMT2AIDO1EGFR | |
| SCHEMBL30639088 | 0.76 | APAF1 (0.48) | POLBMEN1KMT2AIDO1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |