Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 8/20 | 0.43 |
| ▸ | IDO1 | P14902 | 7/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 4/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639071 | 1.00 | TDO2 (0.43) | TDO2IDO1IDO2AGTR1AGTR2 | |
| SCHEMBL26614198 | 0.89 | TDO2 (0.47) | TDO2IDO1IDO2AGTR1AGTR2 | |
| SCHEMBL30639102 | 0.85 | TDO2 (0.42) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL9222336 | 0.82 | TDO2 (0.63) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL31382842 | 0.80 | TDO2 (0.46) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL26857585 | 0.80 | TDO2 (0.46) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL9115282 | 0.75 | IDO1 (0.55) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL30639070 | 0.72 | IDO1 (0.58) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL14503718 | 0.69 | MAPT (0.44) | AGTR1AGTR2 | |
| SCHEMBL26614098 | 0.68 | IDO1 (0.67) | TDO2IDO1IDO2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |